Artwork from the Whistler House Museum of Art's permanent collection is on display in the galleries of the historic house, which spans all three floors of the beautifully restored Federal and Greek Revival home.

The focus of the Museum's collection is late nineteenth-century and early twentieth-century American representational art, with special emphasis on the artists of New England.

Among the artists represented are James McNeill Whistler, William McGregor Paxton, Frank W. Benson, Marie Danforth Page, Thomas Bailey Lawson, William Preston Phelps, Aldro T. Hibbard, Sarah Wyman Whitman, Elizabeth Morse Walsh, William Morris Hunt, John Singer Sargent, and Arshile Gorky.